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It relaxes blood vessels, increasing the blood and oxygen supply to your heart. It is effective in the long-term treatment of angina associated with coronary artery disease. Generic isosorbide mononitrate is available.<br> <h3><u>What should I tell my health care provider before I take this medicine?</u></h3><br> They need to know if you have any of these conditions:<br> • anemia<br> • dizziness or fainting spells when rising from a sitting position<br> • glaucoma<br> • head injury, recent stroke, or bleeding in the brain<br> • low blood pressure, or low blood volume<br> • previous heart attack<br> • overactive thyroid<br> • stomach or intestinal disease<br> • an unusual or allergic reaction to isosorbide dinitrate, other medicines, foods, dyes, or preservatives<br> • pregnant or trying to get pregnant<br> • breast-feeding<br> <h3><u>How should I take this medicine?</u></h3><br> Take isosorbide tablets by mouth. Follow the directions on the prescription label. Unless your prescriber or health care professional tells you otherwise for the regular tablets (Ismo®), take the first dose when you get up in the morning and the second dose about 7 hours later. Swallow regular tablets with a drink of water. Unless your prescriber or health care professional tells you otherwise for the sustained-release tablets (Imdur®), take once a day when you get up in the morning. Swallow sustained-release tablets whole; do not crush or chew. Take isosorbide mononitrate on an empty stomach, 1 hour before or 2 hours after food. Take at regular intervals. Try to take your doses at the same time each day, and continue to take them even if you feel better. It can take several weeks or longer to see the full effects of this medicine. Do not stop taking except on your prescriber's advice. Do not take your medicine more often than directed.<br> <br> Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.<br> <h3><u>What if I miss a dose?</u></h3><br> If you miss a dose, take it as soon as you can. If it is almost time for your next dose (less than 6 hours for regular tablets or 12 hours for sustained-release tablets), take only that dose. Do not take double or extra doses.<br> <h3><u>What drug(s) may interact with isosorbide mononitrate?</u></h3><br> • acetylcholine<br> • alcohol<br> • aspirin<br> • beta-blockers, often used for high blood pressure or heart problems<br> • histamine<br> • medicines for colds and breathing difficulties<br> • medicines for high blood pressure<br> • medicines for mental problems or psychotic disturbances<br> • medicines for pain<br> • sildenafil (Viagra®)<br> • tadalafil (Cialis®)<br> • vardenafil (Levitra®)<br> • water pills<br> <br> Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) should not be taken with this medication to avoid severe side effects including very low blood pressure and other complications.<br> <br> Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.<br> <h3><u>What side effects may I notice from taking isosorbide mononitrate?</u></h3><br> Side effects that you should report to your prescriber or health care professional as soon as possible:<br> • bluish discoloration of lips, fingernails, or palms of hands<br> • dizziness or fainting<br> • dry mouth<br> • irregular heartbeat, palpitations<br> • low blood pressure<br> • skin rash<br> • sweating<br> • the feeling of extreme pressure in the head<br> • unusual tiredness or weakness<br> <br> Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):<br> • flushing of the face or neck<br> • headache<br> • nausea, vomiting<br> <h3><u>What should I watch for while taking isosorbide mononitrate?</u></h3><br> Check your heart rate and blood pressure regularly while you are taking isosorbide mononitrate. Ask your prescriber or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your prescriber or health care professional if you feel your medicine is no longer having any effect.<br> <br> You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how isosorbide mononitrate affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, and increase flushing and rapid heartbeats. Avoid alcoholic drinks.<br> <br> Do not stop taking isosorbide mononitrate suddenly or your symptoms may get worse. Ask your prescriber or health care professional how to gradually reduce the dose.<br> <h3><u>Where can I keep my medicine?</u></h3><br> Keep out of the reach of children.<br> <br> Store between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.<br> </p> ,<h2>What is/are Imdur Extended-Release Tablets?</h2> <p>ISOSORBIDE MONONITRATE is a vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. This medicine is used to prevent chest pain caused by angina. It will not help to stop an episode of chest pain. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.</p> <h2>What should I tell my health care providers before I take this medicine?</h2> <p>They need to know if you have any of these conditions:</p> <ul> <li>previous heart attack or heart failure </li> <li>an unusual or allergic reaction to isosorbide mononitrate, nitrates, other medicines, foods, dyes, or preservatives </li> <li>pregnant or trying to get pregnant </li> <li>breast-feeding</li> </ul> <h2>How should I use this medicine?</h2> <p>Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not crush, cut, or chew. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.</p> <p>Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.</p> <p>Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.</p> <p>Note: This medicine is only for you. Do not share this medicine with others.</p> <h2>What if I miss a dose?</h2> <p>If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <p>Do not take this medicine with any of the following:</p> <ul> <li>medicines used to treat erectile dysfunction (ED) like sildenafil, tadalafil, and vardenafil </li> </ul> <p>This medicine may also interact with the following:</p> <ul> <li>medicines for high blood pressure </li> <li>other medicines for angina or heart failure</li> </ul> <p>This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.</p> <h2>What side effects may I notice from this medicine?</h2> <p>Side effects that you should report to your doctor or health care professional as soon as possible:</p> <ul> <li>bluish discoloration of lips, fingernails, or palms of hands </li> <li>irregular heartbeat, palpitations </li> <li>low blood pressure </li> <li>nausea, vomiting </li> <li>persistent headache </li> <li>unusually weak or tired </li> </ul> <p>Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):</p> <ul> <li>flushing of the face or neck </li> <li>rash</li> </ul> <p>This list may not describe all possible side effects.</p> <h2>What should I watch for while using this medicine?</h2> <p>Check your heart rate and blood pressure regularly while you are taking this medicine. 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